Bioorganic and Medicinal Chemistry Letters p. 765 - 770 (1998)
Update date:2022-08-05
Topics:
Escribano, Ana
Ezquerra, Jesus
Pedregal, Concepcion
Rubio, Almudena
Yruretagoyena, Belen
Baker, S. Richard
Wright, Rebecca A.
Johnson, Bryan G.
Schoepp, Darryle D.
(2S,4S)-2-Amino-4-(4,4-diphenylbut-1-yl)-pentane-1,5-dioic acid 1m, is a novel metabotropic glutamate receptor (mGluR) antagonist with insignificant ionotropic affinity. It is a selective antagonist of negatively-coupled cAMP-linked mGluRs with no effect
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