Asymmetric Total Synthesis of (+)-Goniopypyrone

DOI: 10.1016/S0040-4039(00)61602-7

Source and publish data:

Tetrahedron Letters p. 7075 - 7076 (1993)

Update date:2022-08-05

Topics:

Authors:

Zhou, Wei-Shan

Yang, Zhi-Cai

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Article abstract of DOI:10.1016/S0040-4039(00)61602-7

An effective asymmetric total synthesis of (+)-goniopypyrone from methyl cinnamate (2) via OsO4 catalytic asymmetric dihydroxylation and highly stereoselective 2-furylcopper addition in eight steps with an overall yield of 20 percent is described.

Full text of DOI:10.1016/S0040-4039(00)61602-7

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