Tetrahedron Letters p. 7677 - 7680 (1993)
Update date:2022-08-03
Topics:
Kim, Kyoung Soon
Qian, Ligang
Use of N,N'-di-(tert-butoxycarbonyl)thiourea 1 in the presence of mercuric chloride provides a very efficient method for the bis-Boc protected guanidine formation of the amino compounds which are highly deactivated either sterically or electronically.
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()Doi:10.1016/j.tet.2009.10.086
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