Isosteric phosphonate analogs of ET-16-OMe. Synthesis and biological evaluation of the enantiomers of 2'-(trimethylammonio)ethyl 4-(hexadecyloxy)- 3-methoxybutanephosphonate and 2'-(trimethylammonio)ethyl 4-(hexadecylthio)- 3-methoxybutanephosphonate

DOI: 10.1021/jm00029a016

Source and publish data:

Journal of Medicinal Chemistry p. 425 - 430 (1994)

Update date:2022-08-03

Topics:

Authors:

Bittman Bittman

Byun Byun

Mercier Mercier

Salari Salari

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00029a016

The enantiomers of two isosteric phosphonate analogs of the ether-linked antitumor agent 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine (ET-18- OMe) were synthesized and evaluated for their cytotoxicity against various mouse leukemic cell lines in v

Full text of DOI:10.1021/jm00029a016

Products guided by the article

Product name:2'-(trimethylammonio)-ethyl-4-(hexadecylthio)-3-methoxybutane phosphonate

Cas No:153413-99-1

R&D Labs maybe for 153413-99-1

Shanghai Longschem Co.,Ltd

Contact:021-36356756

Address:Room601,Building No.14,280 Yangcheng Road,Shanghai
Tianjin Te-An Chemtech Co., Ltd.(expird)

Contact:+86-22-65378638

Address:A5-8, No.80 Haiyun Street, TEDA
Wuxi D-Stone International Co., Ltd.

Contact:+86-510-82740567

Address:21F Hengtong Int'l Centre, 215Zhongshan Road, Wuxi, Jiangsu,China
Shenzhen JYMed Technology Co.,Ltd.

website:http://www.jymedtech.com

Contact:+86-755-26612112

Address:1#8,9/F, Biomedicine innovation Industrial Park, No.14, Jinhui Road, Pingshan Sistrict, Shenzhen, China
Tianjin Tongde Biological Technology Co., Ltd.

Contact:86-22-23309138

Address:Room 402, bulidingE3 Detection certification park, XiQingDistrict, Tianjin City

Relevant to this article

Mixed 5-HT_1A/D-2 Activity of a New Model of Arylpiperazines: 1-Aryl-4-<3-(1,2-dihydronaphthalen-4-yl)-n-propyl>piperazines. 1. Synthesis and Structure-Activity Relationships

Doi:10.1021/jm00027a012
(1994)
Doi:10.1007/BF02895778
(1959)
Regiodivergent access to five- and six-membered benzo-fused lactams: Ru-catalyzed olefin hydrocarbamoylation

Doi:10.1021/ja411913e
(2014)
Annulation with methyl 4-(triphenylphosphoranylidene)acetoacetate. Application to the synthesis of a 1,3-benzenedicarboxylate derivative

Doi:10.1080/00397919308013806
(1993)
Palladium-catalyzed reactions of allyl acetates with N-substituted 4-trimethylstannyl-1,2,3,6-tetrahydropyridines

Doi:10.1134/S1070428013120269
()
Novel hybrids derived from aspirin and chalcones potently suppress colorectal cancer in vitro and in vivo

Doi:10.1039/C8MD00284C
(2018)

Article Doi