Chiral synthons for CARBA-β-D-ribonucleosides. Synthesis of CARBA-4- deoxypyrazofurin and isomeric CARBA-4-deaza-oxoformycin analogues

Article abstract of DOI:10.1080/15257779908043088

Multi-step transformation of enantiomerically pure synthons, (1S,2S,3R,4R)-(4-hydroxymethyl-2,3-isopropylidenedioxy-1-cyclopentyl) methyl butyrate {(-)-5} and (1R,5R,6R,7S)-6,7-(isopropylidenedioxy)-3- oxabicyclo[3.2.1]octane-2-one {(+)-11} into carba-4-deoxypyrazofurin 1 and isomeric carba-4-deaza-oxoformycin 2 analogues is presented.