Synthesis of oligonucleotides containing N2-(5-carboxypentyl)-2'-deoxyguanosine and 5-[2-(4'-methyl-2,2'-dipyrid-4-yl-carboxamido)ethylthio]-2'-deoxyuridi ne

Article abstract of DOI:10.1016/S0040-4039(00)61684-2

Synthesis of 2'-deoxyguanosine tethered at N-2 to a carboxypentyl group and 2'-deoxyuridine tethered through C-5 to a bipyridine is described. The modified nucleosides were converted to the corresponding phosphoramidites and incorporated into mono- and di