Dianilinophthalimides: Potent and selective, ATP-competitive inhibitors of the EGF-receptor protein tyrosine kinase

DOI: 10.1021/jm00033a019

Source and publish data:

Journal of Medicinal Chemistry p. 1015 - 1027 (1994)

Update date:2022-08-04

Topics:

Authors:

Trinks Trinks

Buchdunger

Furet Furet

Kump Kump

Mett Mett

Meyer Meyer

Muller Muller

Regenass

Rihs Rihs

Lydon Lydon

Traxler Traxler

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00033a019

Dianilinophthalimides represent a novel class of inhibitors of the EGF- receptor protein tyrosine kinase with a high degree of selectivity versus other tyrosine and serine/threonine kinases. Steady-state kinetic analysis of compound 3, which showed potent

Full text of DOI:10.1021/jm00033a019

Products guided by the article

Product name:dimethyl 4,5-bis(4-iodoanilino)phthalate

Cas No:153600-96-5

R&D Labs maybe for 153600-96-5

MiHecb Bio-Tech Co., Ltd.

Contact:+86-0592 5353131

Address:No.56 Guani Road Software Park 2,Siming District
Shandong Yubin Chemical CO.,LTD

website:http://www.yukaichem.com/en.html

Contact:+86-536-8865336

Address:binhai economic development zone，262737 shangdong，china
Water Chemical Co.,LTD

Contact:+86-21-6856-1349 523-87676172

Address:No16 . BinJiang Road . Taixing Economy Developing Area .JiangSu Province . China
Shandong Zhongcheng Barium Salt Co., Ltd

Contact:+86-15725732638

Address:No.29 baoxi road, hi-tech zone, zibo, shandong
Wuhan Chemchemical Co., Ltd.(expird)

Contact:15973022782

Address:7-5-6218,Incubation Centre,Guandong Industry Park, East Lake High-Tech Development Zone,Wuhan City.

Relevant to this article

Doi:10.1016/S0040-4039(01)99639-X
(1966)
Cluster Chemistry. Part 92. Directed Syntheses and Crystal Structures of <<μ-PPh2C2>>*CH2Cl2, <(μ-PPh2C2C2)> and (μ-PPh2)(μ-CO)2(CO)14>*CH2Cl2

Doi:10.1039/DT9930003313
(1993)
New thalidomide-resembling dicarboximides target ABC50 protein and show antileukemic and immunomodulatory activities

Doi:10.3390/biom9090446
(2019)
Tetrahydroquinolinyl phosphinamidates and phosphonamidates enhancing tolerance towards drought stress in crops via interaction with ABA receptor proteins

Doi:10.1016/j.bmc.2020.115725
(2020)
Enantioselective aza-Henry reaction for the synthesis of (S)-levamisole using efficient recyclable chiral Cu(II)-amino alcohol derived complexes

Doi:10.1016/j.molcata.2015.08.009
(2015)
Vinylborane formation in rhodium-catalyzed hydroboration of vinylarenes. Mechanism versus borane structure and relationship to silation

Doi:10.1021/ja00082a006
(1994)

Article Doi