Synthesis and pharmacological activities of novel cyclic disulfide and cyclic sulfide derivatives as hepatoprotective agents

DOI: 10.1248/cpb.41.1066

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1066 - 1073 (1993)

Update date:2022-08-05

Topics:

Authors:

Ito Ito

Ota Ota

Suhara Suhara

Tabashi Tabashi

Kawashima

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Article abstract of DOI:10.1248/cpb.41.1066

In order to search for anti-hepatitis drugs, we synthesized a series of eight- and nine-membered cyclic disulfides (1) and six- and seven-membered cyclic sulfides (2) and evaluated them for ability to reduce mortality in the model of acute hepatic failure

Full text of DOI:10.1248/cpb.41.1066

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