An asymmetric synthesis of a C2 symmetric tetrasubstituted biaryl: 2,2′-Dihydroxy-6,6′-dimethyl-1,1′-biphenyl, a stable chiral system

Article abstract of DOI:10.1016/S0040-4039(00)61579-4

An asymmetric synthesis of enantiomerically pure bisphenol (S)-12 was accomplished in 40-50% by an oxazoline mediated biaryl coupling.