Magnetic Resonance in Chemistry p. 255 - 257 (1994)
Update date:2022-07-30
Topics:
Clarke, David
Mares, Richard W.
McNab, Hamish
Riddell, Frank G.
Reaction of 3-aminopyrazole (1) with chloroacetyl chloride gives a mixture of 3-amino-1- and -2-(chloroacetyl)pyrazole (2 and 3), both of which rearrange in the solid-state to 3-(chloroacetamido)pyrazole (4) over a period of a few days.The course of the rearrangements was monitored directly by CP/MAS NMR and indirectly by 1H NMR spectroscopy; the results suggest that the mechanism involves 3 -> 2 -> 4. - Keywords: NMR, 13C CP/MAS, 1H Solid-state rearrangement, 3-Amino-1- and -2-(chloroacetyl)pyrazole
View MoreJinan Aery Pharmaceutical Co,.Ltd
Contact:+8653181263406
Address:1-1916,Building1 Fenghuang SOHO,Fenghuang Road,High-tech Zone,Jinan,Shandong
HANGZHOU PANYU CHEMICAL CO.,LIMITED
Contact:+86-571-86578491
Address:Rm 605, NO.1870 Binsheng Road,Binjiang Dist, Hangzhou, China
Geen Chemical Technology Co., Ltd
Contact:86-769-21660847
Address:1408, Yingfeng Commercial Center, Nancheng District
ShangHai Ruiyi Medical Technology Co.,Ltd.
Contact:+86-21-54718086
Address:No951 Jianchuan RD，Minhang District
Jiangsu Wanlong Chemical Co., Ltd.
website:http://www.wanlongchem.com
Contact:+86-511-86810993 0086-511-8681 0888;
Address:Quanzhou Town, Danyang City, Jiangsu
Doi:10.1021/ol500051e
(2014)Doi:10.1016/S0040-4039(00)73177-7
(1994)Doi:10.1021/ja4104292
(2014)Doi:10.1021/ja00089a008
(1994)Doi:10.1002/ejoc.201300934
(2013)Doi:10.1021/jm401868d
(2014)
