A synthesis of enantiomerically pure 3- and 3,3-disubstituted pyrrolidines

DOI: 10.1016/S0040-4039(00)79942-4

Source and publish data:

Tetrahedron Letters p. 973 - 976 (1994)

Update date:2022-08-04

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Authors:

Westrum Westrum

Meyers Meyers

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Article abstract of DOI:10.1016/S0040-4039(00)79942-4

Enantiomerically pure bicyclic lactam 1, derived from (S)-phenylglycinol, underwent diastereoselective mono- and dialkylation affording substituted lactams 2 and 3 bearing tertiary and quaternary stereocenters. Reduction with LiAlH₄ furnished N

Full text of DOI:10.1016/S0040-4039(00)79942-4

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