Metal complexes of macrocyclic ligands. Part XXXVII. Synthesis of heteroditopic bis-macrocycles and their potential for preparing heterobinuclear metal complexes

Article abstract of DOI:10.1002/hlca.19940770105

A new and generally applicable synthetic path for the preparation of heteroditopic bis-macrocycles using tri-N-protected tetraazacycloalkanes as building blocks and bromoacetyl bromide as bridging reagent is described. In the first step, bromoacetyl bromi