New dual inhibitors of neutral endopeptidase and angiotensin-converting enzyme: Rational design, bioavailability, and pharmacological responses in experimental hypertension

DOI: 10.1021/jm00034a005

Source and publish data:

Journal of Medicinal Chemistry p. 1070 - 1083 (1994)

Update date:2022-08-04

Topics:

Authors:

Fournie-Zaluski

Coric Coric

Turcaud Turcaud

Rousselet

Gonzalez

Barbe Barbe

Pham Pham

Jullian Jullian

Michel Michel

Roques Roques

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00034a005

In the treatment of cardiovascular diseases, it could be of therapeutic interest to associate the hypotensive effects resulting from the inhibition of angiotensin II formation, ensured by endothelial angiotensin-converting enzyme (ACE), with the diuretic

Full text of DOI:10.1021/jm00034a005

Products guided by the article

Product name:2-[1-(3,4-Difluoro-phenyl)-ethyl]-malonic acid diethyl ester

Cas No:155943-49-0

R&D Labs maybe for 155943-49-0

Beyond Pharmaceutical Co., Ltd

Contact:+86-571-8195-3185

Address:No. 13-1, Liansheng Road, Yuhang District
Huangshi Meifeng Chemical Co.,ltd.

Contact:+86-714-6516706

Address:1941-4-3#,Hubin Avenue,Huangshi,Hubei,China
Zhonghao (dalian) Research and Design Institute of Chemical Industry Co., Ltd

Contact:+86 411 84674606

Address:201, Huangpu Road , Shahekou District, Dalian ,116023-China
Daicel Chiral Technologies (China)CO.,LTD

Contact:021-5046-0086*8

Address:Part C, FL 5, the 16th Building, No. 69, XiYa Road, WaiGaoQiao Free Trade Zone, Shanghai, 200131, P.R.China
Chongqing Werlchem Fine Chemical Co. Ltd

Contact:+86-23-67521957

Address:NO.15,Fortune Road,Yubei District,401121,Chongqing,China

Relevant to this article

A mild and fast continuous-flow trifluoromethylation of coumarins with the CF₃ radical derived from CF₃SO₂Na and TBHP

Doi:10.1039/c5ob01516b
(2015)
Synthesis and Charactirisation of Zirconium Complexes with the Diphosphinophosphide Ligands ^-P(CH2CH2PR2)2 (R = Me or Et); Crystal Structure of Bispentachlorohydridodizirconium(IV)

Doi:10.1039/DT9940000977
(1994)
Synthesis and preliminary evaluation of 2-arylhydroxyquinoline derivatives for tau imaging

Doi:10.1002/jlcr.3133
(2014)
Syntheses of 5-dialkylamino-1,2-oxazoles from N,N-dialkyl-β-amino-α,β,γ,δ-unsaturated thioamides

Doi:10.1007/BF00811850
(1994)
Face Selection in Claisen Rearrangements

Doi:10.1021/jo00091a010
(1994)
Metal-organodiphosphonate chemistry: Hydrothermal syntheses and structures of Zn(II) and Cd(II) coordination polymers with xylyldiphosphonate ligands

Doi:10.1016/j.ica.2013.12.003
(2014)

Article Doi