New dual inhibitors of neutral endopeptidase and angiotensin-converting enzyme: Rational design, bioavailability, and pharmacological responses in experimental hypertension

DOI: 10.1021/jm00034a005

Source and publish data:

Journal of Medicinal Chemistry p. 1070 - 1083 (1994)

Update date:2022-08-04

Topics:

Authors:

Fournie-Zaluski

Coric Coric

Turcaud Turcaud

Rousselet

Gonzalez

Barbe Barbe

Pham Pham

Jullian Jullian

Michel Michel

Roques Roques

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Article abstract of DOI:10.1021/jm00034a005

In the treatment of cardiovascular diseases, it could be of therapeutic interest to associate the hypotensive effects resulting from the inhibition of angiotensin II formation, ensured by endothelial angiotensin-converting enzyme (ACE), with the diuretic

Full text of DOI:10.1021/jm00034a005

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