Archiv der Pharmazie p. 233 - 236 (1994)
Update date:2022-07-30
Topics:
Kostka
Porada
Graczyk
As a result of the reaction of salicylic amide with PCl3 and POCl3 2-chloro-2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one (1) and its 2-oxide 2 are obtained. Compounds 1 and 2 form amides with amines in 2-position. Antineoplastic action of the derivatives containing the bis(2-chloroethyl)amide group in 2-position was found.
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(1994)
