A non-infringing route for enantioselective synthesis of antiepileptic agent lacosamide

DOI: 10.1055/s-0033-1339901

Source and publish data:

Synthesis p. 3383 - 3386 (2013)

Update date:2022-09-26

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Authors:

Wadavrao, Sachin B.

Narikimalli, Ashritha

Narsaiah, A. Venkat

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Article abstract of DOI:10.1055/s-0033-1339901

A non-infringing route for enantioselective synthesis of lacosamide has been developed. The synthesis started from commercially available acrylic acid and was completed in eight steps using Sharpless asymmetric dihydroxylation as a key step with an overal

Full text of DOI:10.1055/s-0033-1339901

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Product name:(S)-3-(benzylamino)-2-hydroxy-3-oxopropyl 4-toluenesulfonate

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