Synthesis of (1 → 6)-linked C-disaccharide derivatives using nitrile oxide/isoxazoline chemistry

Article abstract of DOI:10.1016/S0040-4039(00)76857-2

A stereocontrolled route to (1 → 6)-hydroxymethylene-linked C-disaccharide derivatives has been developed based on cycloaddition of pyranose 1-carbonitrile oxides to 5,6-dideoxyhex-5-enofuranoses and reductive hydrolytic cleavage of the resulting 2-isoxazolines.