
Tetrahedron p. 12859 - 12868 (1995)
Update date:2022-08-05
Topics:
Lygo, Barry
A 'one pot' method for the preparation of N-acyl-2-methylaziridines is described, and the utility of these compounds in the C-acylation of dianions derived from β-ketoesters investigated. Application of the methodology to the synthesis of the polyketide natural product yangonin is also described.
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