Gold(I)-catalyzed asymmetric aldol reactions of isocyanoacetic acid derivatives with fluoroaryl aldehydes

Article abstract of DOI:10.1016/0040-4020(95)00893-D

The catalytic asymmetric synthesis of stereochemically defined fluoro-phenylserines is reported. In the title reaction, when methyl isocyanoacetate is employed, the number of fluorine atoms in the phenyl ring of benzaldehyde controls stereochemical outcom