Synthesis and mitogenic activity of chiral lipopeptide WS1279 and its derivatives

DOI: 10.1248/cpb.41.1965

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1965 - 1970 (1993)

Update date:2022-09-26

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Authors:

Kurimura

Ochiai Ochiai

Achiwa Achiwa

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Article abstract of DOI:10.1248/cpb.41.1965

Optically active lipopeptide derivatives have been synthesized by the use of chiral glycerol derivatives. Lipopeptide WS1279 derivatives with (R)- glycerol moieties showed a higher mitogenic activity than those with the (S)- configuration. Various N-prote

Full text of DOI:10.1248/cpb.41.1965

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