
Tetrahedron Letters p. 2573 - 2576 (1994)
Update date:2022-07-29
Topics:
Muratake, Hideaki
Abe, Itsuko
Natsume, Mitsutaka
A 12-step total synthesis of (+/-)-duocarmycin SA (1) was achieved from a readily available pyrrole 3 by way of 7,10/11,14 and 18, using a SnCl2-mediated reaction of a singlet oxygen adduct 6 with 5, as well as the Heck and Mitsunobu reactions on 9 and 16 as key steps.
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Doi:10.1021/jm00311a051
(1968)Doi:10.1021/ja01167a046
(1950)Doi:10.1002/jhet.5570350140
(1998)Doi:10.1021/ja01019a014
(1968)Doi:10.1021/acs.orglett.7b02380
(2017)Doi:10.1016/S0040-4020(01)81110-8
(1994)