
Tetrahedron p. 3113 - 3122 (1994)
Update date:2022-07-29
Topics:
Wanner, Klaus Th.
Paintner, Franz F.
Compound 5 is a new α-amidoalkylation reagent for the asymmetric synthesis of 2-substituted piperidines.Its chiral auxiliary 3 is derived from camphoric acid and designed for an asymmetric induction mechanism featuring precomplexation as the decisive step
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