Selective homologation of ketones and aldehydes with diazoalkanes promoted by organoaluminum reagents

Article abstract of DOI:10.1055/s-1994-25682

Organoaluminum-promoted single homologation or ring expansion of ketones and aldehydes with diazoalkanes has been described, and among various organoaluminium reagents, exceptionally bulky methylaluminum bis(2,6-di-tert-butyl-4-methylphenoxide) (MAD) is found to be highly effective for the selective homologation of various ketones and aldehydes.