
Journal of Organic Chemistry p. 3113 - 3122 (1994)
Update date:2022-07-29
Topics: Oxidation NMR spectroscopy Enantioselective Hydrogenation Stereochemistry Reduction Chromatography Total synthesis Diastereoselective Protecting group Cycloaddition Chiral Auxiliary Dehydration Organometallic chemistry
Keck, Gary E.
Palani, Anandan
McHardy, Stanton F.
The macrolide (+)-carbonolide B, the aglycon of the antibiotic carbomycin B, was synthesized via a convergent sequence.A key step of the approach is the union of aldehyde 6 with stannane 7 in the presence of MgBr2*OEt2 as Lewis acid to afford the C1-C9 fr
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