Synthesis of Enantiomerically pure N-Fmoc-S-Mob-(S)-α-Amino-ε-mercaptohexanoic Acid and its use in Solid Phase Peptide Synthesis

Article abstract of DOI:10.1016/0040-4039(94)85200-6

Enantiomerically pure N-Fmoc-S-Mob-(S)-α-amino-ε-mercaptohexanoic acid (Amh) was synthesized in an efficient three step process from (L)-lysine via nucleophilic displacement of the pyridinium salt.An efficient method for Fmoc protection without any racemi