Towards the total synthesis of ambruticin: Preparation of the fully functionalised righ-hand portion using the Intramolecular Silyl-Modified Sakurai (ISMS) annulation

DOI: 10.1055/s-1996-4185

Source and publish data:

Synthesis p. 297 - 304 (1996)

Update date:2022-08-03

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Authors:

Marko Marko

Bayston Bayston

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Article abstract of DOI:10.1055/s-1996-4185

The concise synthesis of the fully functionalised right-hand dihydropyran subunit of the antifungal antibiotic ambruticin (1), using the ISMS annulation as the key-step, is described.

Full text of DOI:10.1055/s-1996-4185

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