Facile, regioselective syntheses of N-alkylated 2,3-diaminopyridines and imidazo[4,5-b]pyridines

Article abstract of DOI:10.1021/jo00109a029

Useful strategies are reported for the differentiation and selective synthetic manipulations of amino groups at the 2- and 3-positions of pyridines. It has been found that 2,3-diaminopyridine reacts with aldehydes under reductive amination conditions to g