Chemoenzymatic synthesis of chiral β-azidoalcohols. Application to the preparation of chiral aziridines and aminoalcohols

Article abstract of DOI:10.1016/0957-4166(94)80084-7

From the microbiological reduction of 3-azido-2-octanone, 3-azido-4-phenyl-2-butanone and 1-azido-1-phenyl-2-propanone, homochiral isomers of the corresponding β-azidoalcohols were prepared. These 'α-bichiral' synthons were used to prepare all the stereoi