Journal of Medicinal Chemistry p. 725 - 732 (1994)
Update date:2022-08-04
Topics:
Graham, Samuel L.
deSolms, S. Jane
Giuliani, Elizabeth A.
Kohl, Nancy E.
Mosser, Scott D.
et al.
Inhibitors of Ras farnesyl-protein transferase are described.These are reduced pseudopeptides related to the C-terminal tetrapeptide of the Ras protein that signals farnesylation.Deletion of the carbonyl groups between the first two residues of the tetrap
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