Napthoo-fused azepines as potent growth hormone secretagogues

DOI: 10.1016/S0960-894X(97)10115-9

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2951 - 2954 (1997)

Update date:2022-08-02

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Authors:

Hansen, Thomas Kruse

Thogersen, Henning

Hansen, Birgit Sehested

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Article abstract of DOI:10.1016/S0960-894X(97)10115-9

Computer guided improvements of known growth hormone secretagogues are reported. These are a new series of napthofused azepines. Structure-activity relationships are different than in the corresponding benzo-fused azepines.

Full text of DOI:10.1016/S0960-894X(97)10115-9

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Product name:[2-(1-Benzyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-ylcarbamoyl)-1,1-dimethyl-ethyl]-carbamic acid tert-butyl ester

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