Synthesis of Cluster Galactosides with High Affinity for the Hepatic Asialoglycoprotein Receptor

DOI: 10.1021/jm00009a014

Source and publish data:

Journal of Medicinal Chemistry p. 1538 - 1546 (1995)

Update date:2022-08-03

Topics:

Authors:

Biessen, Erik A.L.

Beuting, Diana M.

Roelen, Harlof C.P.F.

Marel, Gijs A. van de

Boom, Jacques H. van

Berkel, Theo J.C. van

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Article abstract of DOI:10.1021/jm00009a014

High-affinity ligands for the asialoglycoprotein receptor, which is uniquely localized on the parenchymal liver cell and recognizes oligoantennary galactosides, might be utilized as homing device to specifically target drugs or genes to paranchymal liver

Full text of DOI:10.1021/jm00009a014

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Product name:5-hydroxy-3-oxapentyl 2',3',4',6'-tetra-O-benzoyl-β-D-galactopyranoside

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