Regioselective Acetylations of Alkyl β-D-Xylopyranosides by Use of Lipase PS in Organic Solvents and Application to the Chemoenzymatic Synthesis of Oligosaccharides

Article abstract of DOI:10.1021/jo00102a029

Aglycon structure and solvent can change the regioselectivity of the acetylation of alkyl β-D-xylopyranosides, catalyzed by lipase PS.The acetylation of methyl β-D-xylopyranoside (3) in acetonitrile gave the 3,4-diacetate 4 exclusively, whereas the reacti