Potent and orally active angiotensin II receptor antagonists with equal affinity for human AT1 and AT2 subtypes

Article abstract of DOI:10.1021/jm00019a004

In order to block the effects induced by the interactions between angiotensin II (AII) and both AT₁ and AT₂ receptors, we have pursued the discovery of orally active non-peptide AII antagonists that exhibit potent and equal affinity