Potent and orally active angiotensin II receptor antagonists with equal affinity for human AT1 and AT2 subtypes

DOI: 10.1021/jm00019a004

Source and publish data:

Journal of Medicinal Chemistry p. 3741 - 3758 (1995)

Update date:2022-07-29

Topics:

Authors:

Chang Chang

Ashton Ashton

Flanagan

Chen Chen

O'Malley

Zingaro Zingaro

Kivlighn

Siegl Siegl

Lotti Lotti

Chang Chang

Greenlee

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Article abstract of DOI:10.1021/jm00019a004

In order to block the effects induced by the interactions between angiotensin II (AII) and both AT₁ and AT₂ receptors, we have pursued the discovery of orally active non-peptide AII antagonists that exhibit potent and equal affinity

Full text of DOI:10.1021/jm00019a004

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