Synthesis and Biological Evaluation of C-3'-Modified Analogs of 9(R)-Dihydrotaxol

DOI: 10.1021/jm00043a005

Source and publish data:

Journal of Medicinal Chemistry p. 2655 - 2663 (1994)

Update date:2022-08-03

Topics:

Authors:

Li, Leping

Thomas, Sheela A.

Klein, Larry L.

Yeung, Clinton M.

Maring, Clarence J.

et al. et al.

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Article abstract of DOI:10.1021/jm00043a005

Taxol (1) is considered a most exciting new drug in cancer chemotherapy.The promising antitumor activity of 9(R)-dihydrotaxol (3) encouraged us to further explore the structure-activity relationship of this new member of the taxane family.Studies indicate

Full text of DOI:10.1021/jm00043a005

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