Design, synthesis and pharmacological evaluation of novel pyrrolizine derivatives as potential anticancer agents

DOI: 10.1016/j.bioorg.2014.01.001

Source and publish data:

Bioorganic Chemistry p. 1 - 7 (2014)

Update date:2022-09-26

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Authors:

Gouda, Ahmed M.

Abdelazeem, Ahmed H.

Arafa, El-Shaimaa A.

Abdellatif, Khaled R.A.

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Article abstract of DOI:10.1016/j.bioorg.2014.01.001

A new series of novel pyrrolizine derivatives has been synthesized and biologically evaluated as potential anticancer agents. The starting compounds, 6-amino-7-cyano-N-(3,5-disubstitutedphenyl)-2,3-dihydro-1H-pyrrolizine-5- carboxamides 11a-b, were reacte

Full text of DOI:10.1016/j.bioorg.2014.01.001

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