
Tetrahedron Letters p. 6495 - 6498 (1994)
Update date:2022-09-26
Topics:
Toyota, Masahiro
Nishikawa, Youichi
Fukumoto, Keiichiro
An expeditious and efficient formal total synthesis of antiviral and antitumor tetracyclic diterpene aphidicolin has been developed. An intramolecular Heck reaction (3→4) and an intramolecular Diels-Alder reaction (7→8) were utilized for the key step of t
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