Ruthenium(II) Complexes with the Atropisomeric Diphosphine 2,2'-Bis(diphenylphosphino)-6,6'-dimethylbiphenyl in the Enantioselective Hydrogenation of Pentane-2,4-dione

DOI: 10.1039/DT9950000049

Source and publish data:

Journal of the Chemical Society, Dalton Transactions p. 49 - 56 (1995)

Update date:2022-08-03

Topics:

Authors:

Mezzetti, Antonio

Tschumper, Andreas

Consiglio, Giambattista

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/DT9950000049

The five-co-ordinate complex > <(S)-biphemp = (S)- 2,2'-bis(diphenylphosphino)-6,6'-dimethylbiphenyl> reacts with pentane-2,4-dione (Hacac) in the presence of NEt3 to give >, which has been isolated in the solid state.The reaction of the chlorohydride > with Hacac gives > and eventually >, which were identified spectroscopically.The relevance of the formation of these new species to the enantioselective hydrogenation of 2,4-diketones to the corresponding diols has been studied by testing > and some of its derivatives as catalyst precursors, also in connection with the use of modifiers such as anhydrous HCl, PPh3, chloride ions, NEt3 and HBF4.The hydrogenation reaction has also been followed under ambient conditions by means of 31P and 1H NMR spectroscopy.The activity and selectivity data confirm that for optimum efficiency two chloride ligands must be present in the catalyst precursor.These data are discussed in view of the assessment of a possible reaction pathway for the catalytic reaction.

Full text of DOI:10.1039/DT9950000049

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:[Ru(H)Cl(PPh₃)((S)-2,2'-bis(diphenylphosphino)-6,6'-dimethylbiphenyl)]

Cas No:160964-80-7

R&D Labs maybe for 160964-80-7

Lanling Hongchuang Flame Retardant Co., Ltd.

Contact:+86-531-68858132

Address:East Huafeichang Road, Cangshan County, Linyi, Shandong, China (Mainland)
Jiangsu Haian Petro chemical Plant

Contact:+86-513-88902723

Address:99, Changjiang West Road, Haian County, Jiangsu
Shanghai Longschem Co.,Ltd

Contact:021-36356756

Address:Room601,Building No.14,280 Yangcheng Road,Shanghai
Shanghai Cheerchem Co., Ltd.

Contact:86-21-50966856

Address:Building 5,300 Chuanzhan Road,Pudong New District,Shanghai
Chengdu Green Young Biopharmaceutical INC

Contact:+86-28-85337952

Address:1-B-26,Tianhe Industry Park, No.1480 of Tianfu Road,Chengdu,P.R.China,610000

Relevant to this article

Synthetic routes towards fluorine-containing amino sugars: Synthesis of fluorinated analogues of tomosamine and 4-amino-4-deoxyarabinose

Doi:10.1002/ejoc.201301614
(2014)
Synthesis of N,N′-disubstituted 3-aminobenzo[c] and [d]azepin-2-ones as potent and specific farnesyl transferase inhibitors

Doi:10.1016/j.bmcl.2003.11.013
(2004)
Synthesis and spectral studies of lanthanides coordination compounds based on N-(diphenylphosphoryl)benzamide. the structure of N-(diphenylphosphoryl) benzamide

Doi:10.1016/j.molstruc.2014.03.069
(2014)
Lithium Salts of 2,4,6-Triaryl-λ⁴-phosphinine anions - A comparison study

Doi:10.1002/ejic.201301259
(2014)
Ultrasound-promoted synthesis of biologically active α- hydroxyphosphonates/hydroxyphosphinates using 1,4-dimethylpiperazine as a catalyst

Doi:10.1080/10426507.2013.843002
(2014)
Understanding the cytotoxic effects of new isovanillin derivatives through phospholipid Langmuir monolayers

Doi:10.1016/j.bioorg.2018.10.029
(2019)

Article Doi