Cell permeable vanX inhibitors as vancomycin re-sensitizing agents

DOI: 10.1016/j.bmcl.2014.03.097

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2535 - 2538 (2014)

Update date:2022-08-05

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Authors:

Muthyala, Ramaiah

Rastogi, Namrata

Shin, Woo Shik

Peterson, Marnie L.

Sham, Yuk Yin

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Article abstract of DOI:10.1016/j.bmcl.2014.03.097

VanX is an induced zinc metallo d-Ala-d-Ala dipeptidase involved in the viable remodeling of bacterial cell wall that is essential for the development of VREF. Here we report two cyclic thiohydroxamic acid-based peptide analogs that were designed, synthes

Full text of DOI:10.1016/j.bmcl.2014.03.097

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