Synthesis of 4-Oxa-2-azapodophyllotoxin, a Novel Analog of the Antitumor Lignan Podophyllotoxin

DOI: 10.1016/S0040-4039(00)78553-4

Source and publish data:

Tetrahedron Letters p. 9401 - 9402 (1994)

Update date:2022-08-03

Topics:

Authors:

Hitotsuyanagi, Yukio

Ichihara, Yoshitatsu

Takeya, Koichi

Itokawa, Hideji

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Article abstract of DOI:10.1016/S0040-4039(00)78553-4

4-Oxa-2-azapodophyllotoxin (5) had been synthesized from sesamol (6). 5 showed significant activity against adriamycin-resistant P-388 leukemia cells.

Full text of DOI:10.1016/S0040-4039(00)78553-4

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