Journal of Medicinal Chemistry p. 3464 - 3476 (1994)
Update date:2022-08-05
Topics: In vitro Chemical analysis in vivo Cell Culture Biological Activity Chemical Compounds Experimental terms Antiproliferative Structure-activity study Cell proliferation
Bergeron, Raymond J.
McManis, James S.
Liu, Charles Z.
Feng, Yang
Weimar, William R.
et al.
A basis set of polyamine analogues was designed and synthesized.These compounds were used to initiate a systematic investigation of the role of chain length, terminal nitrogen alkyl group size, and symmetry of the methylene backbone in the antineoplastic
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