Acetylation of α-cyano-o-tolunitrile: Reinvestigation and convenient synthesis of isoquinolines

Article abstract of DOI:10.1080/00397919508011362

The product from the diacetylation of α-cyano-o-tolunitrile has now been assigned as an isocoumarin derivative. This is readily transformed into various 1-substituted-3-methylisoquinoline-4-carbonitriles by reaction with oxygen, nitrogen, carbon and hydrogen nucleophiles.

Full text of DOI:10.1080/00397919508011362

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Acetylation of α-Cyano-o-
tolunitrile: A Reinvestigation
and Convenient Synthesis of
Isoquinolines
L. W. Deady a & N. H. Quazi a
a Chemistry Department , La Trobe University ,
Bundoora, Vic. 3083, Australia
Published online: 23 Sep 2006.
To cite this article: L. W. Deady & N. H. Quazi (1995) Acetylation of α-Cyano-o-
tolunitrile: A Reinvestigation and Convenient Synthesis of Isoquinolines, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 25:3, 309-320, DOI: 10.1080/00397919508011362
To link to this article: http://dx.doi.org/10.1080/00397919508011362
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