Tetrahedron Letters p. 3683 - 3687 (2014)
Update date:2022-07-30
Topics:
Ahmed, Naseem
Pathe, Gulab Khushalrao
Venkata Babu
Sn(IV)Cl4 catalyst provided a rapid and efficient deprotection method for the phenolic THP and MOM ethers and sequel intramolecular Friedel-Crafts alkylation reaction of THP and MOM protected chalcone epoxides under mild conditions. The reaction took 2-3 min to give the products in excellent yield (90-98%) at 0 °C without affecting the other functional groups.
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