Organocatalytic enantioselective allylic alkylation of MBH carbonates with β-keto esters

DOI: 10.1039/c4ob00682h

Source and publish data:

Organic and Biomolecular Chemistry p. 5071 - 5076 (2014)

Update date:2022-07-31

Topics:

Authors:

Kamlar Kamlar

Hybelbauerova

Cisarova

Vesely Vesely

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c4ob00682h

The highly stereoselective allylic alkylation of Morita-Baylis-Hillman carbonates with β-ketoesters catalysed by β-ICD is described. The corresponding products containing two adjacent quaternary and tertiary carbon centers were obtained in good yields with high diastereoselectivity (up to 10 : 1 dr) and enantioselectivity (up to 95% ee).

Full text of DOI:10.1039/c4ob00682h

Products guided by the article

Product name:isopropyl (R)-1-((R)-2-(methoxycarbonyl)-1-phenylallyl)-2-oxocyclopentane-1-carboxylate

Cas No:1617568-08-7

R&D Labs maybe for 1617568-08-7

Rugao Jinling Chemical Co., Ltd.(expird)

Contact:0086-513-68005586

Address:Lianluo new village huangshi town Rugao city Jiangsu Province.
Nantong Kaixin Pharma Chemical Co.,Ltd.

Contact:86-513-85250786

Address:2-1103 Huachen Mansion, 111 Gongnong Road,Nantong, Jiangsu, China
Shanghai Hanshare Industry Co.,Ltd.

Contact:86 21 20960688

Address:RM902-903,Building E, Wanda Plaza,No.26,Zhoukang Road, Pudong District, Shanghai, China
Wuhan Chemchemical Co., Ltd.(expird)

Contact:15973022782

Address:7-5-6218,Incubation Centre,Guandong Industry Park, East Lake High-Tech Development Zone,Wuhan City.
Jiangsu Zenji Pharmaceuticals LTD

Contact:+86-025-83172562; +1-224-888-1133(USA)

Address:No.5 Xinmofan Road

Relevant to this article

Microwave irradiation: A green approach for the synthesis of functionalized: N -methyl-1,4-dihydropyridines

Doi:10.1039/c8ra09155b
(2018)
One-pot synthesis of non-symmetric tetraoxanes with the H₂O₂/MTO/fluorous alcohol system

Doi:10.1016/S0040-4039(03)01472-2
(2003)
Formation of a hetero[3]rotaxane by a dynamic component-swapping strategy

Doi:10.1039/c4cc03612c
(2014)
Ultrasound- and microwave-assisted synthesis of (E)-1-aryl-3-[2-(piperidin- 1-yl)quinolin-3-yl]prop-2-en-1-ones and (E)-1-aryl-3-[2-(pyrrolidin-1-yl) quinolin-3-yl]prop-2-en-1-ones, and their antimicrobial activity

Doi:10.1134/S1070363214060309
(2014)
Copper-catalyzed direct arylselenation of anilines by C-H bond cleavage

Doi:10.1002/adsc.201400804
(2015)
Visible-light-driven copper-catalyzed aerobic oxidative cascade cyclization of N-tosylhydrazones and terminal alkynes: Regioselective synthesis of 3-arylcoumarins

Doi:10.1039/c9cc01801h
(2019)

Article Doi