Tetrahedron Letters p. 6309 - 6312 (2003)
Update date:2022-07-31
Topics:
Iskra, Jernej
Bonnet-Delpon, Danièle
Bégué, Jean-Pierre
1,2,4,5-Tetraoxanes, potent antimalarial drugs, were selectively synthesized in fluorous alcohols (2,2,2-trifluoroethanol-TFE and 1,1,1,3,3,3-hexafluoro-2-propanol-HFIP). A use of these solvents enabled for the first time a one-pot synthesis of non-symmet
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