Bioorganic and Medicinal Chemistry Letters p. 1671 - 1676 (1997)
Update date:2022-07-30
Topics:
Lin, Yang-I
Bitha, Panayota
Sakya, Subas M.
Strohmeyer, Timothy W.
Li, Zhong
Lee, Ving J.
Lang Jr., Stanley A.
Yang, Youjun
Bhachech, Niraja
Weiss, William J.
Petersen, Peter J.
Jacobus, Nilda V.
Bush, Karen
Testa, Raymond T.
Tally, Francis P.
A series of twelve highly active aminomethyl-THF 1β-methylcarbapenems 3a-1 were synthesized. Of these, carbapenems 3a-f demonstrated a spectrum of antimicrobial activity comparable to those of imipenem and meropenem with the exception of only moderate anti-pseudomonal activity. Most importantly, they demonstrated moderate intrinsic oral activity against an E. coli infection in mice.
View MoreBeijing Zhongshuo Pharmaceutical T & D Co.,Ltd
Contact:0086-10-64430626
Address:ea No 16, HEPINGLI,DONGCHENG DISTRICT,BEIJING,P.R.CHINA.
Liaoning Yufeng Chemical Co.,Ltd.
Contact:86-0419-3418888
Address:The metallurgical industrial zone,shoushan town, Liaoyang, Liaoning, China
Anhui New Star Pharmaceutical Development Co., Ltd
Contact:013956922763
Address:Floor 3, F9A, F Workshop, No.110 Kexue Road, High-Tech Development Zone, Hefei, Anhui ,China
Contact:+86 755 26588093
Address:No.9 Linkong West Street, Hengdian Street, Huangpi District, Wuhan City, China.
Contact:+86-22-83718541
Address:32th Floor, Rongqiao Center Intersection of Changjiang Road and Nankai Six Road Nankai District Tianjin 300102, China
Doi:10.1016/j.ejmech.2015.08.041
(2015)Doi:10.1515/chempap-2015-0018
(2015)Doi:10.1021/jo501144v
(2014)Doi:10.1080/00397911.2016.1270324
(2017)Doi:10.1016/j.steroids.2014.05.013
(2014)Doi:10.1016/S0040-4020(97)10048-5
(1997)
