Stereocontrolled intramolecular cyclization of ω-tributylstannyl ether aldehydes. Synthesis of the 6·7·7·6 ring system of polycyclic ethers

Article abstract of DOI:10.1016/0040-4039(91)85042-4

The BF₃·OEt₂ mediated intramolecular cyclization of the γ-oxo-substituted allylic tin (1) having an aldehyde group at the terminus of the carbon chain proceeded in a stereocontrolled manner to give the 7-membered β-hydroxy cyclic eth