Regiospecific Intramolecular Ring-Closure of Heterocumulene-Substituted Indoles: Formation of γ-Carbolines and Pyrimidoindoles.

DOI: 10.1016/0040-4039(94)02399-V

Source and publish data:

Tetrahedron Letters p. 953 - 956 (1995)

Update date:2022-08-05

Topics: Intramolecular Indoles Ring-Closure Formation Regiospecific Heterocumulene

Authors:

Molina, Pedro

Alcantara, Julian

Lopez-Leonardo, Carmen

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Article abstract of DOI:10.1016/0040-4039(94)02399-V

2-(Indol-2-yl)ethyl heterocumulenes undergo ring-closure under acid, basic and thermal conditions to give either dihydro γ-carbolines or dihydropyrimido<3,4-a>indoles in a completeley regiospecific fashion.The mode of cyclization strongly depends on the c

Full text of DOI:10.1016/0040-4039(94)02399-V

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