Tetrahedron Letters p. 825 - 828 (1995)
Update date:2022-08-05
Topics:
Schuerman, Marla A.
Keverline, Kathryn I.
Hiskey, Richard G.
A two step synthesis involving the use of a chiral template, benzyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholine-carboxylate (5a), provides orthogonally protected L-Gla (9) in 60percent overall yield (>99percent ee), with no resolution required.
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Doi:10.1039/c3ra45660a
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(1995)
