Asymmetric Synthesis of S-(+)-4-Amino-5-hexynoic Acid

DOI: 10.1016/0957-4166(94)00380-T

Source and publish data:

Tetrahedron Asymmetry p. 239 - 244 (1995)

Update date:2022-09-26

Topics:

Authors:

McAlonan, Helena

Stevenson, Paul J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0957-4166(94)00380-T

4-Amino-5-hexynoic acid is efficiently synthesised in eight steps (overall yield 10percent) from commercially available (S)-glutamic acid.The key step was conversion of an aldehyde to an acetylene using diethylmethyldiazophosphonate.

Full text of DOI:10.1016/0957-4166(94)00380-T

Products guided by the article

Product name:(S)-(+)-1-(2',4'-dimethoxybenzyl)-5-ethynyl-2-pyrrolidinone

Cas No:162285-17-8

R&D Labs maybe for 162285-17-8

Weifang Jahwa Chemical Co.,Ltd

Contact:0086-536-8897731,8897730

Address:No.5166 East Dongfeng Street,Weifang,Shandong,China
MTT Pharma & Bio-technology Co.,Ltd(expird)

Contact:+86-21-58407925

Address:Room2019, Building C, Tomson Center, No.158, Zhang Yang Road, Shanghai, China
Puyang Huicheng Electronic Material Co., Ltd

website:http://huichengchem.weba.testwebsite.cn/index_en.html

Contact:+86-393-8910800

Address:West Section Shengli Road, Puyang457000, China
Shanghai Bojing Chemical Co., Ltd.

Contact:021-37122233

Address:6F Buildiing 11,No.388,Baifu Road,District Fengxian.Shanghai, China.
Nanjing Habo Medical Technology Co., Ltd.

Contact:025－85769882

Address:No.108. Ganjiabian east. Qixia District .Nanjing

Relevant to this article

Anti-cancer applications of titanocene-functionalised nanostructured systems: An insight into cell death mechanisms

Doi:10.1002/chem.201400300
(2014)
Chiral Bis(oxazolidine)pyridine-copper-catalyzed enantioselective friedel-crafts alkylation of indoles with nitroalkenes

Doi:10.1055/s-0033-1340311
(2014)
On the Mannich bases of acetonyltheobromines. 1. Synthesis of some derivatives of 1-acetonyltheobromine as the raw material for Mannich-condensationa as well as some bis-acetonyltheobromeine compounds

Doi:10.1002/ardp.19673000204
(1967)
SYNTHESIS OF 2,5-DISUBSTITUTED 1,3,4-OXADIAZOLES FROM TRICHLOROMETHYLARENES AND ACYLHYDRAZINES

Doi:10.1007/BF01169843
(1994)
Isothiazoles. Part IV. Cycloaddition reactions of diaryl-oxazolones and munchnones to 3-diethylamino-4-(4-methoxyphenyl)-isothiazole 1,1-dioxide: A new synthesis of triarylpyrroles

Doi:10.1016/0040-4020(94)01110-L
(1995)
Synergistic gold(I)/trimethylsilyl catalysis: Efficient alkynylation of N,O-acetals and related pro-electrophiles

Doi:10.1002/adsc.201400169
(2014)

Article Doi