Stereochemical consequences of the Lewis acid-promoted 3-aza-cope rearrangement of N-alkyl-N-allyl enamines

Article abstract of DOI:10.1016/S0040-4020(01)86707-7

Internal and relative asymmetric induction were examined for the electrophile promoted 3-aza-Cope rearrangement of substituted N-alkyl-N-allyl enamines. In general, internal asymmetric induction was highly variable, and was dependent both upon the nature