Application of Sodium Amalgam Reductive Elimination of Allylic Dibenzoates to the Total Synthesis of 5(S)-12(R) Leukotriene B4

DOI: 10.1016/0040-4039(93)85078-B

Source and publish data:

Tetrahedron Letters p. 6489 - 6492 (1993)

Update date:2022-07-29

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Authors:

Solladie, Guy

Urbano, Antonio

Stone, Guy B.

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Article abstract of DOI:10.1016/0040-4039(93)85078-B

A stereoselective synthesis of 5(S)-12(R) LTB₄ is described in this paper using a novel reaction, the sodium amalgam induced reductive elimination of allylic dibenzoates for the selective synthesis of the E,E,Z-triene moiety.The creation of the

Full text of DOI:10.1016/0040-4039(93)85078-B

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